Agammaglobulinemia and Chronic Lymphocytic Leukemia

Case Reports1 April 1956AGAMMAGLOBULINEMIA AND CHRONIC LYMPHOCYTIC LEUKEMIAROBERT T. S. JIM, M.D., EDWARD H. REINHARD, M.D.ROBERT T. S. JIM, M.D., EDWARD H. REINHARD, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-4-790 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany reports on agammaglobulinemia have appeared in the medical literature since 1952,1-24 but there is only one report of two patients with this disease in association with chronic lymphocytic leukemia.25 The following case report describes another occurrence of agammaglobulinemia in a patient who has chronic lymphocytic leukemia.CASE REPORTA 63 year old white male chemist had been in apparently excellent health until August, 1950, when the diagnosis of chronic lymphocytic leukemia was made on a routine blood examination. He was hospitalized at the Johns Hopkins Hospital, where this diagnosis was confirmed. Several months later he was given x-ray therapy...Bibliography1. Bruton OC: Agammaglobulinemia, Pediatrics 9: 722, 1952. CrossrefMedlineGoogle Scholar2. BrutonAptGitlinJaneway OCLDC: Absence of serum gamma globulins, Am. J. Dis. Child. 84: 632, 1952. Google Scholar3. JanewayAptGitlin CALD: Agammaglobulinemia, Tr. A. Am. Physicians 66: 200, 1953. MedlineGoogle Scholar4. KeidanMcCarthyHaworth SEKJC: Fatal generalized vaccinia with failure of antibody production and absence of serum gamma globulin, Arch. Dis. Childhood 28: 110, 1953. CrossrefMedlineGoogle Scholar5. Jean R: Hipo o a-gamma globulinemia aislada en el nino, Prensa pediat. 4: 91, 1953. Google Scholar6. Jean R: Hypo- ou agamma-globulinemie isolee chez l'enfant, Presse méd. 61: 828, 1953. MedlineGoogle Scholar7. Zinneman H: Agammaglobulinemia, Medical Grand Rounds, V. A. Hospital, Minneapolis 11: 12 (Aug. 21) 1953. Google Scholar8. 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GrantWallace GHWD: Agammaglobulinemia, Lancet 267: 671, 1954. CrossrefMedlineGoogle Scholar15. Good RA: Agammaglobulinemia, Bull. Univ. Minneapolis and Minnesota Med. Foundation 26: 1, 1954. Google Scholar16. Good RA: Clinical investigations in patients with agammaglobulinemia, J. Lab. and Clin. Med. 44: 803, 1954. Google Scholar17. RohnBehnkeBond RJRHWH: Acquired agammaglobulinemia with hypersplenism, J. Lab. and Clin. Med. 44: 918, 1954. Google Scholar18. SaslawWall SRL: Adult agammaglobulinemia, J. Lab. and Clin. Med. 44: 925, 1954. Google Scholar19. YoungWolfson IIWQ: Idiopathic and acquired symptomatic agammaglobulinemia, J. Lab. and Clin. Med. 44: 959, 1954. Google Scholar20. Editorial: Agammaglobulinemia, J. A. M. A. 156: 1084, 1954. CrossrefMedlineGoogle Scholar21. ArendsCoonradRundles TEVRW: Serum proteins in Hodgkin's disease and malignant lymphoma, Am. J. Med. 16: 833, 1954. CrossrefMedlineGoogle Scholar22. ZinnemanHallHeller HHWHBI: Acquired agammaglobulinemia, J. A. M. A. 156: 1390, 1954. CrossrefMedlineGoogle Scholar23. Martin NH: Agammaglobulinemia, a congenital defect, Lancet 267: 1094, 1954. CrossrefMedlineGoogle Scholar24. RosecanTrobaughDanforth MFWH: Agammaglobulinemia in the adult, Am. J. Med. 19: 303, 1955. CrossrefMedlineGoogle Scholar25. BremMorton TAME, cited by Zinneman, H. H., et al.22 Google Scholar26. RundlesCoonradArends RWEVT: Serum proteins in leukemia, Am. J. Med. 16: 842, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, Missouri*Received for publication January 18, 1955.From the Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.†This work was supported, in part, by Grant H-22 from the National Heart Institute of the National Institutes of Health. 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