Key points are not available for this paper at this time.
Case Reports1 April 1956AGAMMAGLOBULINEMIA AND CHRONIC LYMPHOCYTIC LEUKEMIAROBERT T. S. JIM, M.D., EDWARD H. REINHARD, M.D.ROBERT T. S. JIM, M.D., EDWARD H. REINHARD, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-4-790 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany reports on agammaglobulinemia have appeared in the medical literature since 1952,1-24 but there is only one report of two patients with this disease in association with chronic lymphocytic leukemia.25 The following case report describes another occurrence of agammaglobulinemia in a patient who has chronic lymphocytic leukemia.CASE REPORTA 63 year old white male chemist had been in apparently excellent health until August, 1950, when the diagnosis of chronic lymphocytic leukemia was made on a routine blood examination. He was hospitalized at the Johns Hopkins Hospital, where this diagnosis was confirmed. Several months later he was given x-ray therapy...Bibliography1. Bruton OC: Agammaglobulinemia, Pediatrics 9: 722, 1952. CrossrefMedlineGoogle Scholar2. BrutonAptGitlinJaneway OCLDC: Absence of serum gamma globulins, Am. J. Dis. Child. 84: 632, 1952. Google Scholar3. JanewayAptGitlin CALD: Agammaglobulinemia, Tr. A. Am. Physicians 66: 200, 1953. MedlineGoogle Scholar4. KeidanMcCarthyHaworth SEKJC: Fatal generalized vaccinia with failure of antibody production and absence of serum gamma globulin, Arch. Dis. Childhood 28: 110, 1953. CrossrefMedlineGoogle Scholar5. Jean R: Hipo o a-gamma globulinemia aislada en el nino, Prensa pediat. 4: 91, 1953. Google Scholar6. Jean R: Hypo- ou agamma-globulinemie isolee chez l'enfant, Presse méd. 61: 828, 1953. MedlineGoogle Scholar7. Zinneman H: Agammaglobulinemia, Medical Grand Rounds, V. A. Hospital, Minneapolis 11: 12 (Aug. 21) 1953. Google Scholar8. Bruton OC: Agammaglobulinemia (congenital absence of gamma globulin): report of a case, M. Ann. District of Columbia 22: 648, 1953. MedlineGoogle Scholar9. YoungWolfson IIWQ: The agammaglobulinemia syndrome in adult men: its differentiation into familial lymphopenic agammaglobulinemia and familial non-lymphopenic dysglobulinemia, Proc. Am. Federation Clin. Research 2: 101, 1954. Google Scholar10. SanfordFavourTribeman JPCBMS: Absence of serum gamma globulins in an adult, New England J. Med. 250: 1027, 1954. CrossrefMedlineGoogle Scholar11. PrasadKoza ASDW: Agammaglobulinemia, Ann. Int. Med. 41: 629, 1954. LinkGoogle Scholar12. Moncke C: Essentielle Agammaglobulinamie, Schweiz. med. Wchnschr. 84: 1033, 1954. MedlineGoogle Scholar13. LangSchettlerWildhack NGR: Über einen Fall von "Agammaglobulinamie" und das verhalten parenteral Zugeführten radioaktiv markierten Gamma-globulins im Serum, Klin. Wchnschr. 32: 856-863, 1954. CrossrefMedlineGoogle Scholar14. GrantWallace GHWD: Agammaglobulinemia, Lancet 267: 671, 1954. CrossrefMedlineGoogle Scholar15. Good RA: Agammaglobulinemia, Bull. Univ. Minneapolis and Minnesota Med. Foundation 26: 1, 1954. Google Scholar16. Good RA: Clinical investigations in patients with agammaglobulinemia, J. Lab. and Clin. Med. 44: 803, 1954. Google Scholar17. RohnBehnkeBond RJRHWH: Acquired agammaglobulinemia with hypersplenism, J. Lab. and Clin. Med. 44: 918, 1954. Google Scholar18. SaslawWall SRL: Adult agammaglobulinemia, J. Lab. and Clin. Med. 44: 925, 1954. Google Scholar19. YoungWolfson IIWQ: Idiopathic and acquired symptomatic agammaglobulinemia, J. Lab. and Clin. Med. 44: 959, 1954. Google Scholar20. Editorial: Agammaglobulinemia, J. A. M. A. 156: 1084, 1954. CrossrefMedlineGoogle Scholar21. ArendsCoonradRundles TEVRW: Serum proteins in Hodgkin's disease and malignant lymphoma, Am. J. Med. 16: 833, 1954. CrossrefMedlineGoogle Scholar22. ZinnemanHallHeller HHWHBI: Acquired agammaglobulinemia, J. A. M. A. 156: 1390, 1954. CrossrefMedlineGoogle Scholar23. Martin NH: Agammaglobulinemia, a congenital defect, Lancet 267: 1094, 1954. CrossrefMedlineGoogle Scholar24. RosecanTrobaughDanforth MFWH: Agammaglobulinemia in the adult, Am. J. Med. 19: 303, 1955. CrossrefMedlineGoogle Scholar25. BremMorton TAME, cited by Zinneman, H. H., et al.22 Google Scholar26. RundlesCoonradArends RWEVT: Serum proteins in leukemia, Am. J. Med. 16: 842, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, Missouri*Received for publication January 18, 1955.From the Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.†This work was supported, in part, by Grant H-22 from the National Heart Institute of the National Institutes of Health. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIncidence and prognostic significance of serum immunoglobulins and paraproteins in patients with chronic lymphocytic leukaemia: another valuable piece of the puzzleCryptococcus neoformans infections in patients with lymphoproliferative neoplasmsPartial reconstitution of humoral immunity and fewer infections in patients with chronic lymphocytic leukemia treated with ibrutinibHypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia: Natural history, clinical correlates, and outcomesImmunoglobulin prophylaxis in hematological malignancies and hematopoietic stem cell transplantationImmunoglobulin prophylaxis in hematological malignancies and hematopoietic stem cell transplantationDisease activity and pretreatment, rather than hypogammaglobulinaemia, are major risk factors for infectious complications in patients with chronic lymphocytic leukaemiaHistorical aspects of chronic lymphocytic leukaemiaHistorical aspects of chronic lymphocytic leukaemiaImpaired synthesis of immunoglobulin in patients with chronic lymphocytic leukemiaChronic Lymphocytic Leukemia Recent Advances in Biology and TreatmentROBERT PETER GALE, M.D., Ph.D., KENNETH A. FOON, M.D.Defective complement activity in chronic lymphocytic leukemiaImmunodeficiencies Associated with Chronic Lymphocytic Leukemia and Non–Hodgkin's LymphomasChronic lymphocytic leukemia: Correlation of clinical course and therapeutic response with in vitro testing and morphology of lymphocytesIMPAIRED IMMUNORESPONSIVENESS IN TUMOR PATIENTSImmune Deficiency States Associated with Malignant Disease in ManTHE ROLE OF THE THYMUS AND BURSA OF FABRICIUS IN THE DEVELOPMENT OF EFFECTOR MECHANISMS*Patterns of Immunological Deficiency in Lymphomas and LeukemiasDANIEL G. MILLER, M.D.Antibodies to Blood Group A and B Substances in ReticulosesAuto-immune Haemolytic Anaemia in some Malignant Systemic DiseasesImmunologic factors and resistance to infection in chronic lymphatic leukemiaQuantitative determination of A2 haemoglobin by paper electrophoresis using tris bufferCIRCULATING ANTIBODIES IN RETICULOSESChronic Lymphocytic Leukemia�ber seltener vorkommende Ver�nderungen der Serumeiwei�-Zusammensetzung bei verschiedenartigen klinischen SyndromenFamilial hypogammaglobulinemia, splenomegaly and leukopeniaTRANSITION OF LYMPHATIC LEUKÆMIA TO RETICULUM CELL SARCOMAHOST-PARASITE RELATIONSHIPS IN PATIENTS WITH DYSPROTEINEMIASHypogammaglobulinemia and chronic lymphatic leukemiaPlasma-Cell MyelomaTHE CLINICAL IMPLICATIONS OF HYPOGAMMAGLOBULINEMIA IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA AND LYMPHOCYTIC LYMPHOSARCOMA*†JOHN E. ULTMANN, WINTHROP FISH, ELLIOTT OSSERMAN, ALFRED GELLHORN, F.A.C.P.AUTO-IMMUNITY IN MAN AND HOMOLOGOUS DISEASE IN MICE IN RELATION TO THE MALIGNANT LYMPHOMASTumours of the thyroid gland in relation to some general concepts of neoplasiaDysproteinemiaDas Bluteiweißbild bei Leukämien und Erkrankungen des lymphatischen Systems 1 April 1956Volume 44, Issue 4Page: 790-796KeywordsChronic lymphocytic leukemiaCryptococcus neoformansFeversHeartLumbar puncturePneumoniaPneumonitisProteinsSputumUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 April 1956 PDF downloadLoading ...
Jim et al. (Sun,) studied this question.