August 4, 2015

Comparison of anti-inflammatory effect of atorvastatin with rosuvastatin in patients of acute coronary syndrome

SKSushant KhuranaManagement Development Institute SGSurabhi GuptaMaharani Laxmi Bai Medical College HBHira Lal BhallaAll India Institute of Medical Sciences Raipur

Structured PICO

Does rosuvastatin 20 mg reduce CRP and LDL cholesterol levels more effectively than atorvastatin 40 mg in patients with acute coronary syndrome?

Population

Patients with acute coronary syndrome

Intervention

Rosuvastatin 20 mg

Comparator

Atorvastatin 40 mg

Outcome

Decrease in C-reactive protein (CRP) and LDL cholesterol levelssurrogate

In patients with acute coronary syndrome, a 4-week course of rosuvastatin 20 mg provides a greater reduction in the inflammatory marker CRP compared to atorvastatin 40 mg.

Abstract

Both atorvastatin (40 mg) and rosuvastatin (20 mg) are effective in decreasing CRP and LDL cholesterol levels even in a short duration of 4 weeks. Rosuvastatin was found to be more effective in decreasing CRP levels.

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Cite This Study

Khurana et al. (Tue,) studied this question.

synapsesocial.com/papers/69d78c69b843b2be9949038f https://doi.org/https://doi.org/10.4103/0976-500x.162011

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