High-intensity intermittent exercise elicited similar central hemodynamic responses compared to moderate continuous exercise in HFREF patients, but with lower oxygen uptake and ventilation.
RCT (n=13)
randomly assigned
Does a single session of high-intensity intermittent exercise elicit different acute hemodynamic responses compared to moderate-intensity continuous exercise in patients with HFrEF?
High-intensity intermittent exercise elicits similar central hemodynamic responses but with lower oxygen uptake and ventilation compared to moderate continuous exercise in patients with HFrEF.
The aim of this study was to compare the acute hemodynamic responses during high-intensity intermittent exercise (HIIE) session compared with moderate-intensity continuous exercise (MICE) session in patients with heart failure and reduced ejection fraction (HFREF). Thirteen patients with HFREF (age, 59 ± 6 years; left ventricular ejection fraction, 27% ± 6%; New York Heart Association class I to III) were randomly assigned to a single session of HIIE (2 × 8 min) corresponding to 30 s at 100% of peak power output (PPO) and 30 s passive recovery intervals or to a MICE (22 min) at 60% of PPO. Gas exchange and central hemodynamic parameters (cardiac bioimpedance) were measured continuously during exercise. Oxygen uptake, stroke volume (SV), cardiac output (CO), and arterio-venous difference (C(a-v)O(2)) were compared. Mean oxygen uptake and ventilation were lower during HIIE vs. MICE. CO, SV, and C(a-v)O(2)) were not different between MICE and HIIE. Optimized HIIE was well tolerated (similar perceived exertion) and no significant ventricular arrhythmias and (or) abnormal blood pressure responses occurred during HIEE session. Compared with MICE, optimized HIIE elicited similar central hemodynamic and C(a-v)O(2) responses in HFREF patients with lower oxygen uptake and ventilation. HIIE may be an efficient exercise training modality in patients with HFREF.
Gayda et al. (Fri,) conducted a rct in Heart failure and reduced ejection fraction (HFREF) (n=13). High-intensity intermittent exercise (HIIE) vs. Moderate-intensity continuous exercise (MICE) (22 min) at 60% of PPO was evaluated on Acute hemodynamic responses (oxygen uptake, stroke volume, cardiac output, and arterio-venous difference). High-intensity intermittent exercise elicited similar central hemodynamic responses compared to moderate continuous exercise in HFREF patients, but with lower oxygen uptake and ventilation.