Is Next-Generation Sequencing feasible and effective for identifying the genetic causes of dilated cardiomyopathy?
Large-scale cohort of patients with dilated cardiomyopathy (DCM)
Next-Generation Sequencing across a broad gene panel of known DCM genes
Genetic causes of DCM and analytical quality/feasibility of Next-Generation Sequencing
Next-Generation Sequencing is a feasible and high-quality tool for clinical genetic diagnostics in patients with dilated cardiomyopathy.
This is to our knowledge, the first study that comprehensively investigated the genetics of DCM in a large-scale cohort and across a broad gene panel of the known DCM genes. Our results underline the high analytical quality and feasibility of Next-Generation Sequencing in clinical genetic diagnostics and provide a sound database of the genetic causes of DCM.
Building similarity graph...
Analyzing shared references across papers
Loading...
Jan Haas
Karen Frese
Barbara Peil
European Heart Journal
University College London
Inserm
Heidelberg University
Building similarity graph...
Analyzing shared references across papers
Loading...
Haas et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69d5721975589c71d767e4bb — DOI: https://doi.org/10.1093/eurheartj/ehu301
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: