Does parental cardiovascular disease predict future cardiovascular events in middle-aged adults?
Middle-aged adults
Parental cardiovascular disease (exposure/risk factor)
Future cardiovascular eventshard clinical
Parental cardiovascular disease is an independent predictor of future cardiovascular events, which can aid in risk stratification for primary prevention in intermediate-risk patients.
Using validated events, we found that parental cardiovascular disease independently predicted future offspring events in middle-aged adults. Addition of parental information may help clinicians and patients with primary prevention of cardiovascular disease, when treatment decisions may be difficult in patients at intermediate risk based on levels of single or multiple risk factors. These data also support further research into genetic determinants of cardiovascular risk.
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Donald M. Lloyd‐Jones
Preventive Cardiology
Byung‐Ho Nam
Boston University
Ralph B. D’Agostino
Wake Forest University
JAMA
National Institutes of Health
Harvard University Press
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Lloyd‐Jones et al. (Tue,) studied this question.
synapsesocial.com/papers/69c08a95a86cbd814171e831 — DOI: https://doi.org/10.1001/jama.291.18.2204