Why the study?
Does parental cardiovascular disease predict future cardiovascular events in middle-aged adults?
Does parental cardiovascular disease predict future cardiovascular events in middle-aged adults?
Parental cardiovascular disease is an independent predictor of future cardiovascular events, which can aid in risk stratification for primary prevention in intermediate-risk patients.
May aid risk stratification when added to models in middle-aged adults; leaves open prospective validation for prevention.
Using validated events, we found that parental cardiovascular disease independently predicted future offspring events in middle-aged adults. Addition of parental information may help clinicians and patients with primary prevention of cardiovascular disease, when treatment decisions may be difficult in patients at intermediate risk based on levels of single or multiple risk factors. These data also support further research into genetic determinants of cardiovascular risk.
No takes yet. Share an insight, caveat, or question.
Lloyd‐Jones et al. (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: