Key result
A parental history of premature coronary heart disease best predicted cardiovascular mortality (P=0.011 for paternal history), whereas family history of stroke or peripheral arterial disease did not.
Why the study?
It was unclear which history of cardiovascular disease (coronary heart disease, stroke, or peripheral arterial disease) in a first-degree family member best predicts cardiovascular mortality.
Does a first-degree family member history of cardiovascular disease predict cardiovascular mortality?
Cohort
Yes
Does a first-degree family member history of cardiovascular disease predict cardiovascular mortality?
p-value: p=0.011
Parental history of premature coronary heart disease is an independent predictor of cardiovascular mortality, emphasizing its importance in cardiovascular risk assessment.
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Parental premature CHD history may refine CV mortality risk assessment; leaves open broader family CVD history utility.
Gharios et al. (2021) reported a cohort. First-degree family member history of cardiovascular disease vs. No family history of cardiovascular disease was evaluated on Cardiovascular mortality (p=0.011). A parental history of premature coronary heart disease best predicted cardiovascular mortality (P=0.011 for paternal history), whereas family history of stroke or peripheral arterial disease did not.
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