The American, British and Dutch responses to unlinked anonymous HIV seroprevalence studies

In this review we wish to describe the responses to proposals for seroprevalence studies in the United States, the United Kingdom, and Netherlands in order to provide background for those nations where the has still to be resolved. The responses differed in these three. In the United States, such studies aroused little debate and were with relative ease. In the United Kingdom, the issue was the of heated debate and was resolved finally in favor of unlinked studies an "opt out" provision. In the Netherlands, the issue has provoked great and has yet to be settled. Such an examination is especially now that the efficacy of early intervention to inhibit the of HIV disease has been demonstrated. The clinical significance of infected individuals may place strains on the alliances that have blinded studies and may create potent ethical challenges to their use.