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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiosynthesis of Erythromycin and RapamycinJames Staunton and Barrie WilkinsonView Author Information Department of Chemistry, Lensfield Road, Cambridge CB2 1EW, UK Bioprocessing Research Unit, GlaxoWellcome Research and Development, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UKCite this: Chem. Rev. 1997, 97, 7, 2611–2630Publication Date (Web):November 10, 1997Publication History Received9 April 1997Revised26 June 1997Published online10 November 1997Published inissue 1 November 1997https://pubs.acs.org/doi/10.1021/cr9600316https://doi.org/10.1021/cr9600316research-articleACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views4709Altmetric-Citations186LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biosynthesis,Chemical structure,Lactones,Metabolism,Peptides and proteins Get e-Alerts
Staunton et al. (1997) studied this question.