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Systolic (SBP), diastolic (DBP) and mean MBP = diastolic + 1/3 (systolic - diastolic) blood pressures were compared as predictors of all causes of death (ALL) and of deaths from atherosclerotic cardiovascular disease (ACVD) in 2480 men, aged 40-59 years, belonging to three cohorts followed up for 20 years. Both univariate analysis, based on distribution of events in age-specific quintile classes of blood pressures, and multivariate analysis, based on the Cox proportional hazards model with five covariates as possible confounders, clearly showed the superiority of SBP over DBP in predicting fatal events; MBP played an intermediate role.
Menotti et al. (Sat,) studied this question.
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