This review discusses the roles and consequences of activation of various protein kinases expressed in the heart, including their involvement in ion handling, contractility, metabolism, and growth.
Intracellular signalling in the heart
Protein kinases
Protein kinases play important roles in intracellular signalling pathways in probably all cells. In the heart, they are involved in the regulation of ion handling, contractility, fuel metabolism and growth. In this review, we discuss the consequences of activation of protein kinases known to be expressed in the heart. We concentrate principally on the following: cyclic AMP-dependent protein kinase, protein kinase C, mitogen-activated protein kinase, Ca2+/calmodulin-dependent protein kinases and pyruvate dehydrogenase kinase.
Building similarity graph...
Analyzing shared references across papers
Loading...
P H Sugden
Waikato Hospital
Marie A. Bogoyevitch
Electrophysiology
Cardiovascular Research
National Institutes of Health
Building similarity graph...
Analyzing shared references across papers
Loading...
Sugden et al. (Sun,) conducted a review in Intracellular signalling in the heart. Protein kinases was evaluated. This review discusses the roles and consequences of activation of various protein kinases expressed in the heart, including their involvement in ion handling, contractility, metabolism, and growth.
synapsesocial.com/papers/6a200937d5e8712fdf65b943 — DOI: https://doi.org/10.1016/s0008-6363(95)00096-8
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: