Subject-specific middiastolic image acquisition improved right coronary artery border definition by 13% (P<0.001) compared to a heart-rate-dependent delay.
Observational (n=15)
Does subject-specific middiastolic image acquisition improve coronary MRA and vessel wall imaging compared to a heart-rate-dependent formula in healthy adults?
Subject-specific middiastolic image acquisition significantly improves 3D coronary MRA border definition and is essential for RCA vessel wall imaging compared to standard heart-rate-dependent formulas.
p-value: p=<0.001
The purpose of this study was to investigate the impact of in-plane coronary artery motion on coronary magnetic resonance angiography (MRA) and coronary MR vessel wall imaging. Free-breathing, navigator-gated, 3D-segmented k-space turbo field echo ((TFE)/echo-planar imaging (EPI)) coronary MRA and 2D fast spin-echo coronary vessel wall imaging of the right coronary artery (RCA) were performed in 15 healthy adult subjects. Images were acquired at two different diastolic time periods in each subject: 1) during a subject-specific diastasis period (in-plane velocity <4 cm/second) identified from analysis of in-plane coronary artery motion, and 2) using a diastolic trigger delay based on a previously implemented heart-rate-dependent empirical formula. RCA vessel wall imaging was only feasible with subject-specific middiastolic acquisition, while the coronary wall could not be identified with the heart-rate-dependent formula. For coronary MRA, RCA border definition was improved by 13% (P < 0.001) with the use of subject-specific trigger delay (vs. heart-rate-dependent delay). Subject-specific middiastolic image acquisition improves 3D TFE/EPI coronary MRA, and is critical for RCA vessel wall imaging.
Kim et al. (Fri,) conducted a observational in Healthy (n=15). Subject-specific middiastolic trigger delay vs. Heart-rate-dependent empirical formula trigger delay was evaluated on Right coronary artery border definition (p=<0.001). Subject-specific middiastolic image acquisition improved right coronary artery border definition by 13% (P<0.001) compared to a heart-rate-dependent delay.