High levels of beta(2)AR overexpression in mice lead to cardiomyopathy and heart failure, though requiring higher expression and having a slower onset than beta(1)AR overexpression.
A high level of beta(2)AR overexpression results in cardiomyopathy and heart failure. The onset was slower and the expression levels of receptors required are much higher than previously described for the beta(1)AR overexpression.
X. Du (Fri,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: