In conscious sedated dogs, the left ventricular diastolic pressure-diameter curve is sigmoidal and influenced by viscous and inertial forces.
The dynamic function of the left ventricle was described in terms of internal diameter, pressure, and flow in conscious sedated dogs at rest and during isoproterenol and metaraminol infusions. The diastolic pressure-diameter curve was sigmoidal in shape, negative in pressure in early diastole, and affected by viscous, and probably inertial, forces.
Horwitz et al. (Wed,) studied this question.
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