Chronic right ventricular pacing in patients with isolated congenital atrioventricular block resulted in a satisfactory mean six-minute walk distance of 546.9 meters, strongly correlating with predicted values (r = 0.907, p = 0.001).
Cross-Sectional (n=61)
No
Effect estimate: r = 0.907
p-value: p=0.001
BACKGROUND: Isolated congenital atrioventricular block (CAVB) is a rare condition with multiple clinical outcomes. Ventricular remodeling can occur in approximately 10% of the patients after pacemaker (PM) implantation. OBJECTIVES: To assess the functional capacity of children and young adults with isolated CAVB and chronic pacing of the right ventricle (RV) and evaluate its correlation with predictors of ventricular remodeling. METHODS: This cross-sectional study used a cohort of patients with isolated CAVB and RV pacing for over a year. The subjects underwent clinical and echocardiographic evaluation. Functional capacity was assessed using the six-minute walk test. Chi-square test, Fisher's exact test, and Pearson correlation coefficient were used, considering a significance level of 5%. RESULTS: A total of 61 individuals were evaluated between March 2010 and December 2013, of which 67.2% were women, aged between 7 and 41 years, who were using PMs for 13.5 ± 6.3 years. The percentage of ventricular pacing was 97.9 ± 4.1%, and the duration of the paced QRS complex was 153.7 ± 19.1 ms. Majority of the subjects (95.1%) were asymptomatic and did not use any medication. The mean distance walked was 546.9 ± 76.2 meters and was strongly correlated with the predicted distance (r = 0.907, p = 0.001) but not with risk factors for ventricular remodeling. (Arq Bras Cardiol. 2014; online.ahead print, PP.0-0) CONCLUSIONS: The functional capacity of isolated CAVB patients with chronic RV pacing was satisfactory but did not correlate with risk factors for ventricular remodeling.
Júnior et al. (Wed,) conducted a cross-sectional in Isolated congenital atrioventricular block (n=61). Chronic right ventricular pacing vs. Predicted normative values was evaluated on Functional capacity assessed by the six-minute walk test distance (r = 0.907, p=0.001). Chronic right ventricular pacing in patients with isolated congenital atrioventricular block resulted in a satisfactory mean six-minute walk distance of 546.9 meters, strongly correlating with predicted values (r = 0.907, p = 0.001).