Key result
Chronic right ventricular pacing in patients with isolated congenital atrioventricular block resulted in a satisfactory mean six-minute walk distance of 546.9 meters, strongly correlating with predicted values (r = 0.907, p = 0.001).
Cross-Sectional (n=61)
No
Effect estimate: r = 0.907
p-value: p=0.001
Chronic right ventricular pacing in patients with isolated congenital atrioventricular block preserves satisfactory functional capacity that closely matches predicted values.
Supports preserved functional capacity with chronic RV pacing in isolated congenital AV block; leaves open need for comparative trials versus physiologic strategies.
BACKGROUND: Isolated congenital atrioventricular block (CAVB) is a rare condition with multiple clinical outcomes. Ventricular remodeling can occur in approximately 10% of the patients after pacemaker (PM) implantation. OBJECTIVES: To assess the functional capacity of children and young adults with isolated CAVB and chronic pacing of the right ventricle (RV) and evaluate its correlation with predictors of ventricular remodeling. METHODS: This cross-sectional study used a cohort of patients with isolated CAVB and RV pacing for over a year. The subjects underwent clinical and echocardiographic evaluation. Functional capacity was assessed using the six-minute walk test. Chi-square test, Fisher's exact test, and Pearson correlation coefficient were used, considering a significance level of 5%. RESULTS: A total of 61 individuals were evaluated between March 2010 and December 2013, of which 67.2% were women, aged between 7 and 41 years, who were using PMs for 13.5 ± 6.3 years. The percentage of ventricular pacing was 97.9 ± 4.1%, and the duration of the paced QRS complex was 153.7 ± 19.1 ms. Majority of the subjects (95.1%) were asymptomatic and did not use any medication. The mean distance walked was 546.9 ± 76.2 meters and was strongly correlated with the predicted distance (r = 0.907, p = 0.001) but not with risk factors for ventricular remodeling. (Arq Bras Cardiol. 2014; [online].ahead print, PP.0-0) CONCLUSIONS: The functional capacity of isolated CAVB patients with chronic RV pacing was satisfactory but did not correlate with risk factors for ventricular remodeling.
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Júnior et al. (2014) conducted a cross-sectional in Isolated congenital atrioventricular block (n=61). Chronic right ventricular pacing vs. Predicted normative values was evaluated on Functional capacity assessed by the six-minute walk test distance (r = 0.907, p=0.001). Chronic right ventricular pacing in patients with isolated congenital atrioventricular block resulted in a satisfactory mean six-minute walk distance of 546.9 meters, strongly correlating with predicted values (r = 0.907, p = 0.001).
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