Are high-risk carotid plaque features on MRI associated with subsequent cerebrovascular events in patients with asymptomatic 50% to 79% carotid stenosis?
Patients with asymptomatic 50% to 79% carotid stenosis
Presence of high-risk plaque features on MRI (thinned or ruptured fibrous caps, intraplaque hemorrhage, larger maximum %lipid-rich/necrotic cores, and larger maximum wall thickness)
Occurrence of subsequent cerebrovascular eventshard clinical
MRI-detected high-risk plaque features in asymptomatic moderate carotid stenosis are associated with future ischemic cerebrovascular events.
Among patients who initially had an asymptomatic 50% to 79% carotid stenosis, arteries with thinned or ruptured fibrous caps, intraplaque hemorrhage, larger maximum %lipid-rich/necrotic cores, and larger maximum wall thickness by MRI were associated with the occurrence of subsequent cerebrovascular events. Findings from this prospective study provide a basis for larger multicenter studies to assess the risk of plaque features for subsequent ischemic events.
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Norihide Takaya
Chun Yuan
Baocheng Chu
Stroke
University of Washington
University of California, Irvine
Juntendo University
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Takaya et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69d7d23111d83f35e5ae2b8d — DOI: https://doi.org/10.1161/01.str.0000204638.91099.91