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February 10, 2006StrokeOpen Access

Association Between Carotid Plaque Characteristics and Subsequent Ischemic Cerebrovascular Events

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Why the study?

Are high-risk carotid plaque features on MRI associated with subsequent cerebrovascular events in patients with asymptomatic 50% to 79% carotid stenosis?

Population

Patients with asymptomatic 50% to 79% carotid stenosis

Design

Cohort

Authors

NTNorihide TakayaKishokai Medical CorporationCYChun YuanCardiac ImagingBCBaocheng ChuNihon University

Discussion

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Implication

MRI high-risk features may aid risk stratification in asymptomatic moderate stenosis; leaves open whether they should guide intervention.

Structured PICO

Are high-risk carotid plaque features on MRI associated with subsequent cerebrovascular events in patients with asymptomatic 50% to 79% carotid stenosis?

P
Population
Patients with asymptomatic 50% to 79% carotid stenosis
I
Intervention
Presence of high-risk plaque features on MRI (thinned or ruptured fibrous caps, intraplaque hemorrhage, larger maximum %lipid-rich/necrotic cores, and larger maximum wall thickness)
O
Outcome
Occurrence of subsequent cerebrovascular eventshard clinical

MRI-detected high-risk plaque features in asymptomatic moderate carotid stenosis are associated with future ischemic cerebrovascular events.

Cite This Study

Takaya et al. (2006) studied this question.

synapsesocial.com/papers/69d7d23111d83f35e5ae2b8dhttps://doi.org/10.1161/01.str.0000204638.91099.91
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Also Consider

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  1. 1Presence of Intraplaque Hemorrhage Stimulates Progression of Carotid Atherosclerotic Plaques2005 · 560 citations
  2. 2Magnetic Resonance Images Lipid, Fibrous, Calcified, Hemorrhagic, and Thrombotic Components of Human Atherosclerosis In Vivo1996 · 670 citations
  3. 3Hypoechoic plaque at US of the carotid artery: an independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study.1998 · 409 citations
  4. 4Ultrasonic Echolucent Carotid Plaques Predict Future Strokes2001 · 578 citations
  5. 5Quantitative Evaluation of Carotid Plaque Composition by In Vivo MRI2004 · 626 citations