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Three species of Antarctic fishes which live in constantly near-freezing waters have a markedly low upper-lethal temperature of 6 degrees C ; this is the lowest upper-lethal temperature reported for any organism. The fishes survive supercooling to -2.5 degrees C. Data on brain metabolism in vitro support the hypothesis that the central nervous system is a primary site of thermal injury.
Somero et al. (Fri,) studied this question.