Continuous intravenous heparin completely prevented deep vein thrombosis compared to no heparin in patients after myocardial infarction (0% vs 29%; p<0.01).
RCT (n=48)
Absolute Event Rate: 0% vs 29%
p-value: p=<0.01
A trial of continuous intravenous heparin in the prevention of deep vein thrombosis was undertaken in 48 patients who had suffered a myocardial infarction. Of the 24 control patients who did not receive heparin seven (29%) developed calf vein thrombosis as detected by the radioactive fibrinogen technique. None of the 24 heparinized patients had any evidence of venous thrombosis. This difference is significant at the 1% level.
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BMJ
Chelsea and Westminster Hospital
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Handley et al. (Sat,) conducted a rct in Myocardial infarction (n=48). Continuous intravenous heparin vs. No heparin was evaluated on Deep vein thrombosis (calf vein thrombosis) (p=<0.01). Continuous intravenous heparin completely prevented deep vein thrombosis compared to no heparin in patients after myocardial infarction (0% vs 29%; p<0.01).