Key result
Continuous intravenous heparin completely prevented deep vein thrombosis compared to no heparin in patients after myocardial infarction.
Why the study?
Does continuous intravenous heparin prevent deep vein thrombosis in patients who have suffered a myocardial infarction?
RCT (n=48)
Does continuous intravenous heparin prevent deep vein thrombosis in patients who have suffered a myocardial infarction?
Continuous intravenous heparin significantly prevents the development of deep vein thrombosis in patients following a myocardial infarction.
Answers are grounded in this paper and cite their sources.
Supports routine heparin prophylaxis post-MI; confirms benefit in this RCT population.
A trial of continuous intravenous heparin in the prevention of deep vein thrombosis was undertaken in 48 patients who had suffered a myocardial infarction. Of the 24 control patients who did not receive heparin seven (29%) developed calf vein thrombosis as detected by the radioactive fibrinogen technique. None of the 24 heparinized patients had any evidence of venous thrombosis. This difference is significant at the 1% level.
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Handley et al. (1972) conducted an RCT in Myocardial infarction (n=48). Continuous intravenous heparin vs. No heparin was evaluated on Deep vein thrombosis (calf vein thrombosis) (p=<0.01). Continuous intravenous heparin completely prevented deep vein thrombosis compared to no heparin in patients after myocardial infarction.
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