Key result
Continuous intravenous heparin completely prevented deep vein thrombosis compared to no heparin in patients after myocardial infarction (0% vs 29%; p<0.01).
Why the study?
Does continuous intravenous heparin prevent deep vein thrombosis in patients who have suffered a myocardial infarction?
RCT (n=48)
Does continuous intravenous heparin prevent deep vein thrombosis in patients who have suffered a myocardial infarction?
Continuous intravenous heparin significantly prevents the development of deep vein thrombosis in patients following a myocardial infarction.
Answers are grounded in this paper and cite their sources.
Supports routine heparin prophylaxis post-MI; confirms benefit in this RCT population.
A trial of continuous intravenous heparin in the prevention of deep vein thrombosis was undertaken in 48 patients who had suffered a myocardial infarction. Of the 24 control patients who did not receive heparin seven (29%) developed calf vein thrombosis as detected by the radioactive fibrinogen technique. None of the 24 heparinized patients had any evidence of venous thrombosis. This difference is significant at the 1% level.
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Handley et al. (1972) conducted an RCT in Myocardial infarction (n=48). Continuous intravenous heparin vs. No heparin was evaluated on Deep vein thrombosis (calf vein thrombosis) (p=<0.01). Continuous intravenous heparin completely prevented deep vein thrombosis compared to no heparin in patients after myocardial infarction (0% vs 29%; p<0.01).
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