Why the study?
Does subcutaneous heparin sodium 5,000 IU reduce the incidence of deep vein thrombosis in patients over age 40 undergoing major operations?
Population
105 patients over age 40 undergoing various major operations
Comparison
Heparin sodium 5,000 international units… vs Placebo subcutaneous injection one hour prior to…
Design
RCT, randomly divided
Follow-up
8 days
Authors
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Low-dose heparin does not reduce postoperative DVT; challenges routine prophylaxis in patients over 40 undergoing major operations.
Does subcutaneous heparin sodium 5,000 IU reduce the incidence of deep vein thrombosis in patients over age 40 undergoing major operations?
Low-dose subcutaneous heparin did not substantially reduce the incidence of DVT compared to placebo in patients over 40 undergoing major operations, though it did not increase blood loss.
Thomas H. Covey (1975) studied this question.
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