The Subcutaneous Use of Heparin in the Prevention of Venous Thrombosis After Myocardial Infarction

View Full Paper

Ask AI

Bookmark

Why the study?

Does subcutaneous heparin prevent venous thrombosis as effectively as intravenous heparin in patients after acute myocardial infarction?

Population

Patients after acute myocardial infarction

Comparison

Heparin administered subcutaneously vs Heparin administered intravenously by an…

Authors

Discussion

Subcutaneous heparin may match IV efficacy for post-MI thrombosis prevention; leaves open confirmation in contemporary randomized trials.

Does subcutaneous heparin prevent venous thrombosis as effectively as intravenous heparin in patients after acute myocardial infarction?

Population

Patients after acute myocardial infarction

Intervention

Heparin administered subcutaneously (initial dose 20,000 to 25,000 units, followed by 10,000 to 12,500 units every 12 hours)

Comparator

Heparin administered intravenously by an infusion pump (30,000 to 40,000 units per day)

Outcome

Incidence of venous thrombosis (assessed via 125I fibrinogen test)surrogate

Subcutaneous heparin is as effective as continuous intravenous heparin for the prevention of venous thrombosis following acute myocardial infarction.

Pitney et al. (1974) studied this question.

View Full Paper

Ask AI

Bookmark