Hereditary Occurrence of the Pre-Excitation (Wolff-Parkinson-White) Syndrome with Re-Entry Mechanism and Concealed Conduction

The hereditary occurrence of the pre-excitation (Wolff-Parkinson-White) syndrome in 3 generations of 1 family is reported. The syndrome was observed in a grandfather. father, in a set of identical twin girls, and in the male of a second set of fraternal twins. Completed abortive circus movements with re-entry into the normal conduction pathway, as well as concealed forward conduction, in the pre-excitation syndrome are demonstrated. The importance of this observation for the understanding of the mechanism of the Wolff-Parkinson-White syndrome is discussed.