Demonstrates the hereditary nature of Wolff-Parkinson-White syndrome across three generations and provides evidence for re-entry and concealed conduction mechanisms.
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Should not change practice; leaves open hereditary transmission and mechanistic implications in pre-excitation.
The hereditary occurrence of the pre-excitation (Wolff-Parkinson-White) syndrome in 3 generations of 1 family is reported. The syndrome was observed in a grandfather. father, in a set of identical twin girls, and in the male of a second set of fraternal twins. Completed abortive circus movements with re-entry into the normal conduction pathway, as well as concealed forward conduction, in the pre-excitation syndrome are demonstrated. The importance of this observation for the understanding of the mechanism of the Wolff-Parkinson-White syndrome is discussed.
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WILLIAM W. HARNISCHFEGER (1959) studied this question.
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