Polio virus infection and actinomycin-D treatment in HeLa cells induce a new class of polysomes containing up to 60 ribosomes, compared to normal polysomes containing over 40 ribosomes.
Polio virus infection induces a new class of larger polysomes in HeLa cells, suggesting a mechanism for protein synthesis with polycistronic RNA.
Absolute Event Rate: 0% vs 0%
HeLa cells normally contain a distribution of polysome sizes, and the largest polysomes contain over 40 ribosomes. After infection with polio virus and actinomycin-D treatment, a new class of polio-induced polysomes are found, some of which contain up to 60 ribosomes. Examinaton of these polysomes suggests a mechanism for protein synthesis with this polycistronic RNA.
Rich et al. (Fri,) reported a other. Polio virus infection and actinomycin-D treatment in HeLa cells induce a new class of polysomes containing up to 60 ribosomes, compared to normal polysomes containing over 40 ribosomes.