Key points are not available for this paper at this time.
Come in! The use of internal oxidants, embedded in the directing group, in CH activation reactions can lead to higher levels of selectivity and reactivity under milder conditions (see examples). An internal oxidant can be defined as a covalent bond within one of the coupling substrates which oxidizes the metal catalyst. This should open up new avenues in the field of CH activation.
Patureau et al. (Thu,) studied this question.