Answers are grounded in this paper and cite their sources.
Come in! The use of internal oxidants, embedded in the directing group, in CH activation reactions can lead to higher levels of selectivity and reactivity under milder conditions (see examples). An internal oxidant can be defined as a covalent bond within one of the coupling substrates which oxidizes the metal catalyst. This should open up new avenues in the field of CH activation.
No takes yet. Share an insight, caveat, or question.
Patureau et al. (2011) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: