What is the prevalence of viral genomes in the myocardium of adults with idiopathic left ventricular dysfunction?
Viral genomes and multiple viral infections are highly prevalent in the myocardium of adults with idiopathic left ventricular dysfunction, suggesting a potential role in the pathogenesis of dilated cardiomyopathy.
Viral genomes were frequently detected in EMBs of patients with systolic left ventricular dysfunction. Our data suggest that myocardial persistence of various viruses, often presenting as multiple infections, may play a role in the pathogenesis of DCM far more frequently than suspected so far.
Kühl et al. (Tue,) studied this question.