Does the CKD-EPI formula provide better estimation of GFR compared to MDRD and Cockcroft-Gault formulas?
CKD-EPI, MDRD, and Cockcroft-Gault formulas for GFR estimation
Absolute bias and accuracy of GFR estimationsurrogate
The CKD-EPI formula provides the best estimation of GFR, though its accuracy is comparable to the MDRD formula, with both being influenced by age and GFR.
The absolute bias of all formulas is influenced by age; CKD-EPI and MDRD are also influenced by GFR. Cockcroft-Gault is additionally influenced by body weight and BMI. In general, CKD-EPI gives the best estimation of GFR, although its accuracy is close to that of the MDRD.
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Michels et al. (Fri,) studied this question.
synapsesocial.com/papers/69d777fd5f9a1dad53490535 — DOI: https://doi.org/10.2215/cjn.06870909
Wieneke M. Michels
Leiden University Medical Center
Diana C. Grootendorst
Medisch Centrum Haaglanden
Marion Verduijn
Leiden University
Clinical Journal of the American Society of Nephrology
University of Amsterdam
Amsterdam UMC Location University of Amsterdam
Leiden University Medical Center
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