Artificial maintenance of AF
Shortening of AERP, reversion of physiological rate adaptation, and increase in rate, inducibility and stability of AFsurrogate
Artificial maintenance of atrial fibrillation causes reversible electrophysiological remodeling that promotes further atrial fibrillation, establishing the foundational concept that 'AF begets AF'.
Artificial maintenance of AF leads to a marked shortening of AERP, a reversion of its physiological rate adaptation, and an increase in rate, inducibility and stability of AF. All these changes were completely reversible within 1 week of sinus rhythm.
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M. C. E. F. Wijffels
C Kirchhof
Rick Dorland
Circulation
Maastricht University
Transnational University Limburg
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Wijffels et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69d5765d62196bac97d9bb0a — DOI: https://doi.org/10.1161/01.cir.92.7.1954
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