Human Heart Failure and Shock Treated by Means of a Mechanical Veno-arterial By-pass without Oxygenation

Case Reports1 November 1961Human Heart Failure and Shock Treated by Means of a Mechanical Veno-arterial By-pass without OxygenationMARVIN BACANER, M.D.MARVIN BACANER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-5-837 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhen coronary circulation is critically reduced cardiac contractile power declines (1-5). When the fall in myocardial contractility results in systemic hypotension, an associated decrease in coronary blood flow may occur and become an important factor in sustaining the hypotensive shock. Previous reports (5-7) described an effective method of interrupting such a vicious cycle in dogs put into shock and heart failure by pulmonary artery constriction. Elevating systemic blood pressure by pumping part of the venous blood (without oxygenation) into a systemic artery (V-A pumping), sharply increased coronary blood flow and resulted in functional recovery with reversal of experimental heart failure...References1. CORDAYBERGMANSCHWARTZSPRITZLERPRINZMETAL ENLRM: Studies on the coronary circulation. IV. The effect of shock on the heart and its treatment. Amer. Heart J. 37: 560, 1949. CrossrefMedlineGoogle Scholar2. TENNANTWIGGERS RCJ: The effect of coronary occlusion on myocardial contraction. Amer. J. Physiol. 112: 351, 1935. CrossrefGoogle Scholar3. CASEBERGLUNDSARNOFF RBESJ: Ventricular function. II. Quantitative relationship between coronary flow and ventricular function with observations on unilateral failure. Circulat. Res. 2: 319, 1954. CrossrefMedlineGoogle Scholar4. GREGG DE: Coronary Circulation in Health and Disease, Lea and Febiger, Philadelphia, 1950, p. 190. Google Scholar5. 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Author, Article, and Disclosure InformationAffiliations: Berkeley, CaliforniaFrom the Donner Laboratory, University of California, Berkeley, California.Supported by United States Public Health Service Grant H-2838.Requests for reprints should be addressed to Marvin Bacaner, M.D., Department of Physiology, The Medical School, University of Minnesota, Minneapolis, Minnesota. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByLeft heart by-pass in cardiac resuscitationDevelopment of Mechanical Heart DevicesArterielle GegenpulsationExtracorporeal support of the circulation by means of venoarterial bypass with an oxygenatorStudies on mechanical assistance to the failing circulationAssisted circulation: An extended concept of cardiopulmonary resuscitationExperimental heart-lung bypass and assisted circulationThe treatment of shock complicating acute myocardial infarctionExtracorporeal oxygenation in puppies and in newborn and fetal lambsEffect of vasopressor drugs on circulatory dynamics in shock following myocardial infarctionShock in Acute Myocardial InfarctionSurgical repair of ruptured papillary muscle complicating posterior myocardial infarctionExtracorporeal circulatory support in cardiac disease 1 November 1961Volume 55, Issue 5Page: 837-843KeywordsBlood flowBlood pressureCoronary arteriesFallsHeart failureHypotensionMedical servicesPulmonary arteriesResearch laboratoriesShock Issue Published: 1 November 1961 PDF DownloadLoading ...