January 18, 2006
Estrogen Carcinogenesis in Breast Cancer
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Abstract
Estrogen exposure is a major determinant of the risk of breast cancer. This article reviews how genotoxic, mutagenic metabolites of estrogen and stimulation of tissue growth by the hormone participate in the pathogenesis of breast cancer.
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Authors
J
James D. Yager
Johns Hopkins University
Nancy E. Davidson
American College of Radiology
Journals
New England Journal of Medicine
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Institutions
Johns Hopkins University
Sidney Kimmel Comprehensive Cancer Center
Public Health Department
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