Functional disability and social adjustment in major depressive disorder were predicted by depression severity, recurrence, lack of full remission, time spent depressed, and comorbidities.
Cohort (n=269)
No
What factors influence social and occupational disability and social adjustment among patients with major depressive disorder?
Functional disability and social adjustment in major depressive disorder are strongly predicted by depression severity, recurrence, and psychiatric comorbidities.
We examined prospectively factors influencing social and occupational disability and social adjustment among patients with major depressive disorder. The Vantaa Depression Study comprises a cohort of psychiatric inpatients and outpatients with major depressive disorder in the city of Vantaa, Finland. We prospectively interviewed 193 of 269 (72%) patients both 6 and 18 months after baseline. Axis I and II diagnoses were assessed via semistructured WHO Schedules for Clinical Assessment in Neuropsychiatry 2.0 and SCID-II interviews. Global disability and social and work adjustment were assessed. Patients' functional disability and social adjustment were alleviated concurrently with recovery from depression during the follow-up. The current level of functioning and social adjustment of a patient with depression was predicted by severity of depression, recurrence before baseline and during follow-up, lack of full remission, and time spent depressed. Comorbid psychiatric disorders, personality traits (neuroticism), and perceived social support had significant influence.
Rytsälä et al. (Tue,) conducted a cohort in Major depressive disorder (n=269). Functional disability and social adjustment in major depressive disorder were predicted by depression severity, recurrence, lack of full remission, time spent depressed, and comorbidities.
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