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August 1, 2006The Journal of Nervous and Mental Disease

Determinants of Functional Disability and Social Adjustment in Major Depressive Disorder

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Key result

Functional disability and social adjustment in major depressive disorder were predicted by depression severity, recurrence, lack of full remission, time spent depressed, and comorbidities.

Why the study?

What factors influence social and occupational disability and social adjustment among patients with major depressive disorder?

Population

193 psychiatric inpatients and outpatients with major depressive disorder in Vantaa, Finland

Design

Cohort

Follow-up

6 and 18 months

Authors

HRHeikki RytsäläFinnish Institute for Health and WelfareTMTarja MelartinHelsinki University HospitalULUlla S. LeskeläFinnish Foundation for Alcohol Studies

Discussion

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Implication

May guide monitoring of MDD severity and remission to limit disability; leaves open whether targeted interventions improve outcomes.

Study Design

Type

Cohort (n=269)

Multicenter

No

Structured PICO

What factors influence social and occupational disability and social adjustment among patients with major depressive disorder?

P
Population
193 psychiatric inpatients and outpatients with major depressive disorder in Vantaa, Finland
O
Outcome
Global disability and social and work adjustmentpatient reported

Functional disability and social adjustment in major depressive disorder are strongly predicted by depression severity, recurrence, and psychiatric comorbidities.

Cite This Study

Rytsälä et al. (2006) conducted a cohort in Major depressive disorder (n=269). Functional disability and social adjustment in major depressive disorder were predicted by depression severity, recurrence, lack of full remission, time spent depressed, and comorbidities.

synapsesocial.com/papers/6a1c54f51567d2fc4d5ff206https://doi.org/10.1097/01.nmd.0000230394.21345.c4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Functioning and Well-being of Depressed Patients1989 · 2,125 citations
  2. 2The functioning and well-being of depressed patients. Results from the Medical Outcomes Study1989 · 2,827 citations
  3. 3Does Social Support Buffer Functional Decline in Elderly Patients With Unipolar Depression?2001 · 123 citations
  4. 4SCAN1990 · 2,548 citations
  5. 5Continuity Is the Main Challenge in Treating Major Depressive Disorder in Psychiatric Care2005 · 112 citations