Do circulating microRNA changes differ between responders and non-responders to Cardiac Resynchronization Therapy in heart failure patients?
Favorable changes in circulating miRNAs regulating fibrosis, apoptosis, and hypertrophy are associated with reverse remodeling in heart failure patients responding to CRT.
In responders, reverse remodelling is associated with favourable changes in miRNAs that regulate cardiac fibrosis, apoptosis, and hypertrophy.
Marfella et al. (Wed,) studied this question.