September 12, 2002Open Access
View Full PaperIncrease in Nocturnal Blood Pressure and Progression to Microalbuminuria in Type 1 Diabetes
Structured PICO
Does an increase in nocturnal systolic blood pressure predict the development of microalbuminuria in persons with type 1 diabetes?
P
Population
Persons with type 1 diabetes
I
Intervention
Increase in systolic blood pressure during sleep (abnormal nocturnal blood pressure pattern)
C
Comparator
Normal decrease in blood pressure during sleep
O
Outcome
Progression to microalbuminuriasurrogate
An abnormal increase in nocturnal systolic blood pressure is an early predictor of microalbuminuria development in patients with type 1 diabetes.
Abstract
In persons with type 1 diabetes, an increase in systolic blood pressure during sleep precedes the development of microalbuminuria. In those whose blood pressure during sleep decreases normally, the progression from normal albumin excretion to microalbuminuria appears to be less likely.
Cite This Study
Lurbe et al. (Thu,) studied this question.