New Curvularin-Type Metabolites from the Hybrid Strain ME 0005 Derived from Penicillium Citreo-viride B. IFO 4692 and 6200

Abstract Four new curvularin-type metabolites (11-α-methoxycurvularin, 11-β-methoxy curvularin, 11,12-dihydroxycurvularin, and 12-hydroxy-10, 11-trans-dehydrocurvularin) have been isolated from the mycelium of the hybrid strain ME 0005 derived from Penicillium citreo-viride B. IFO 4692 and 6200. And β-hydroxycurvularin, the biologically active principle from Alternaria tomato, was identified as 11-β-hydroxycurvularin.