Does a history of depression or psychotropic medication use increase the risk of myocardial infarction?
Depression is associated with an increased risk of myocardial infarction, and the apparent risk associated with psychotropic medications is likely confounded by the underlying depression.
These data suggest that a history of dysphoria and a major depressive episode increase the risk of MI. The association between psychotropic medication use and MI is probably a reflection of the primary relationship between depression and MI.
Pratt et al. (Sun,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: