Biventricular pacing in a 22-year-old with repaired congenital heart disease and dilated cardiomyopathy improved ventricular dP/dt by 14% and fractional area of change by 125% at one month.
Case Report (n=1)
Biventricular, alternative, and multisite pacing are currently being explored to improve cardiac function among patients with medically refractory, end-stage dilated cardiomyopathies. Although, due to inherent myocardial abnormalities, patients with repaired congenital heart defects may be at a greater risk than others to develop heart failure, often requiring cardiac transplantation. The efficacy of biventricular pacing among these patients is unknown. This report presents a patient with successfully repaired congenital heart disease in infancy who developed a symptomatic dilated cardiomyopathy at 22 years of age. Following biventricular pacing, systemic ventricular function showed a 14% improvement in ventricular dP/dt. One month later, subjective symptoms improved and cardiac ultrasound illustrated a 125% increase in fractional area of change. Exercise stress testing showed a 17% improvement in aerobic work capacity.
Rodriguez‐Cruz et al. (Thu,) conducted a case report in Dilated cardiomyopathy associated with congenital heart disease (n=1). Biventricular pacing was evaluated on Ventricular dP/dt, fractional area of change, and aerobic work capacity. Biventricular pacing in a 22-year-old with repaired congenital heart disease and dilated cardiomyopathy improved ventricular dP/dt by 14% and fractional area of change by 125% at one month.