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A rare previously undescribed malignant lymphoma of the histiocytic type (reticulum cell sarcoma), showing an unusual morphological pattern and an atypical clinical behavior, is presented. The most striking histologic feature was a pronounced fibrosis with a peculiar compartmentalization of the tumor tissue. Clinically, survivals up to almost 7 years have been observed despite the fact that in all but one case only local excision or local excision followed by local radiotherapy, with or without prior staging, was carried out. Four patients died with disseminated lymphoma 21, 24, 49, and 56 months after the clinical onset. The remaining 5 patients are alive from 12 to 81 months. The disease was initially localized to the axilla in 6 patients, to the cervical chain in 2, and to the inguinal region in one. It seems that malignant lymphoma of the histiocytic type with sclerosis or “sclerosing reticulum cell sarcoma” has a slower rate of growth and a lesser degree of aggressiveness than the corresponding non-sclerosing tumors.
Rosas-Uribe et al. (Sat,) studied this question.