Arthritis, Inflammatory Bowel Disease, and Histocompatibility Antigens

Editorial Notes1 June 1977Arthritis, Inflammatory Bowel Disease, and Histocompatibility AntigensA. S. RUSSELL, M.B., B.CH., F.R.C.P.(C), M.R.C.P.A. S. RUSSELL, M.B., B.CH., F.R.C.P.(C), M.R.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-86-6-820 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptArthritis and chronic inflammatory bowel disease may coexist in the same patient much more often than could be expected by chance alone. The arthritis seen is of two readily distinguishable types: a migratory peripheral synovitis associated with clinically active bowel disease, and an axial arthropathy generally indistinguishable from sporadic ankylosing spondylitis (1, 2). The synovitis usually reflects active bowel disease and may be relieved, for example, by a total colectomy for ulcerative colitis, but the spondylitis is not related to the extent or severity of the intestinal disease and frequently antedates it. Histocompatibility testing on these patients has improved our...References1. ANSELLWIGLEY BR: Arthritic manifestations in regional enteritis. Ann Rheum Dis 23:64-72, 1964 CrossrefMedlineGoogle Scholar2. ACHESON E: An association between ulcerative colitis, regional enteritis, and ankylosing spondylitis. Q J Med 29:489-499, 1960 MedlineGoogle Scholar3. MALLASMACKINTOSHASQUITH EPP: Histocompatibility antigens in inflammatory bowel disease. Their clinical significance and their association with arthropathy with special reference to HLA-B27 (W27). Gut 17:906-910, 1976 CrossrefMedlineGoogle Scholar4. BREWERTON D: HLA-B27 and the inheritance of susceptibility to rheumatic disease. Arthritis Rheum 19:656-668, 1976 CrossrefMedlineGoogle Scholar5. WRIGHTWATKINSON VG: Sacro-iliitis and ulcerative colitis. Br Med J 2:675-680, 1965 CrossrefMedlineGoogle Scholar6. MACREAWRIGHT IV: A family study of ulcerative colitis with particular reference to ankylosing spondylitis and saroiliitis. Ann Rheum Dis 32:16-20, 1973 CrossrefMedlineGoogle Scholar7. HASLOCKMACREAWRIGHT IIV: Arthritis and intestinal diseases: a comparison of two family studies. Rheumatol Rehabil 13:135-140, 1974 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine The University of Alberta Edmonton, Alberta Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTherapie der extraintestinalen CED-ManifestationenThe burden of inflammatory bowel disease in EuropeTherapie der extraintestinalen CED-ManifestationenInflammatory Bowel DiseaseTreatment of Extraintestinal Manifestations in Inflammatory Bowel DiseaseASSOCIATED DISORDERS AND SPECIAL MANAGEMENT PROBLEMS OF ULCERATIVE COLITISGenetics of inflammatory bowel diseaseAssociation of extraintestinal manifestations of inflammatory bowel disease in a province of western Hungary with disease phenotype: Results of a 25-year follow-up studyInflammatory Bowel Disease2 The immunogenetics of the seronegative spondyloarthropathiesHLA-B27 and the Seronegative SpondyloarthropathiesGenetics of inflammatory bowel disease.Rheumatic manifestations of inflammatory bowel diseaseSpondylodiscitis and pseudarthrosis in a patient with enteropathic spondyloarthropathy.Inflammatory Bowel Disease in Japan: Studies of Epidemiology and EtiopathogenesisAnalysis of Restriction Fragment Length Polymorphisms in Rheumatic DiseasesHistocompatibility typing in the seronegative spondyloarthropathies: A surveyThe spondylitis of inflammatory bowel diseaseReferencesSacroiliitis and HLA. A clinical and genetical study.Rheumatic Disease Associations with HLA AntigensGenetics of inflammatory bowel disease 1 June 1977Volume 86, Issue 6Page: 820-821KeywordsAnkylosing spondylitisArthritisColectomyHistocompatibilityInflammatory arthritisInflammatory bowel diseaseMajor histocompatibility antigensPatientsSpondylitisUlcerative colitis Issue Published: 1 June 1977 PDF downloadLoading ...