Ethanol, chlorpromazine, and hypertonicity multiply miniature end-plate potential frequency independently of calcium, implying a final common pathway for transmitter secretion requiring little or no calcium.
The findings suggest a final common pathway for transmitter secretion that requires little or no calcium.
Ethanol multiplies miniature end-plate potential frequency independently of calcium ion concentrations and also multiplies calcium-dependent depolarization-evoked quantal release, to the same extent. This result implies a final common pathway, requiring little or no calcium, for both kinds of transmitter secretion. Chlorpromazine and hypertonicity act similarly to ethanol, but also depress depolarization-secretion coupling.
Quastel et al. (Fri,) reported a other. Ethanol, chlorpromazine, and hypertonicity was evaluated on Transmitter secretion (miniature end-plate potential frequency and depolarization-evoked quantal release). Ethanol, chlorpromazine, and hypertonicity multiply miniature end-plate potential frequency independently of calcium, implying a final common pathway for transmitter secretion requiring little or no calcium.
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