July 10, 2012

Heart Failure in Severe Aortic Valve Stenosis: Prognostic Impact of Left Ventricular Ejection Fraction and Mean Gradient on Outcome After Transcatheter Aortic Valve Implantation

MGMichael GotzmannElectrophysiology PRPia RahlmannBG University Hospital Bergmannsheil Bochum THTobias HehnenBG University Hospital Bergmannsheil Bochum

Structured PICO

Does low gradient and/or reduced LVEF worsen outcomes in patients with severe aortic stenosis undergoing TAVI?

Population

Patients with severe aortic stenosis undergoing Transcatheter Aortic Valve Implantation (TAVI)

Intervention

Transcatheter Aortic Valve Implantation (TAVI)

Comparator

Patients with preserved LVEF/high gradient

Outcome

Outcome after TAVI

Low gradient and/or reduced LVEF are associated with worse outcomes after TAVI in patients with severe aortic stenosis, highlighting their importance in risk stratification.

Abstract

Severe aortic stenosis with low gradient and/or reduced LVEF is associated with worse outcome after TAVI compared with aortic stenosis with preserved LVEF/high gradient. The evaluation of these haemodynamic parameters may help to improve risk stratification in patients undergoing TAVI.

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