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July 10, 2012European Journal of Heart Failure54 citations

Heart Failure in Severe Aortic Valve Stenosis: Prognostic Impact of Left Ventricular Ejection Fraction and Mean Gradient on Outcome After Transcatheter Aortic Valve Implantation

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MGMichael GotzmannPRPia RahlmannTHTobias Hehnen

Structured PICO

Does low gradient and/or reduced LVEF worsen outcomes in patients with severe aortic stenosis undergoing TAVI?

P
Population
Patients with severe aortic stenosis undergoing Transcatheter Aortic Valve Implantation (TAVI)
I
Intervention
Transcatheter Aortic Valve Implantation (TAVI)
C
Comparator
Patients with preserved LVEF/high gradient
O
Outcome
Outcome after TAVI

Low gradient and/or reduced LVEF are associated with worse outcomes after TAVI in patients with severe aortic stenosis, highlighting their importance in risk stratification.

Abstract

Severe aortic stenosis with low gradient and/or reduced LVEF is associated with worse outcome after TAVI compared with aortic stenosis with preserved LVEF/high gradient. The evaluation of these haemodynamic parameters may help to improve risk stratification in patients undergoing TAVI.

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Cite This Study

Gotzmann et al. (2012) studied this question.

synapsesocial.com/papers/69effa644f6a06657c21dffahttps://doi.org/10.1093/eurjhf/hfs108
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heart Failure in Aortic Stenosis — Improving Diagnosis and Treatment2003 · 48 citations
  2. 2Left ventricular systolic and diastolic function in aortic stenosis: Prognostic value after valve replacement and underlying mechanisms1997 · 146 citations
  3. 3Aortic Stenosis1968 · 718 citations
  4. 4Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology2005 · 11,386 citations
  5. 5Left ventricular function before and following aortic valve replacement.1977 · 205 citations