Treatment of an infected implantable cardioverter defibrillator with oral fusidic acid and rifampin for 3 months without device removal resulted in no infection recurrence over 24 months.
Case Report (n=1)
Does oral fusidic acid and rifampin without device removal prevent infection recurrence in a patient with an infected implantable cardioverter defibrillator?
Oral antibiotics (fusidic acid and rifampin) successfully treated an ICD pocket infection without requiring device extraction, with no recurrence at 24 months.
Infection of an implantable cardioverter defibrillator developed 2 weeks after implantation, presenting with fever, swelling, redness, and tenderness of the skin above the generator site. A cloxacillin resistant coagulase‐negative staphylococcus was repeatedly cultured from the abdominal wall pocket fluid. The infection was successfully treated with a combination of two antibiotics, fusidic acid and rifampin, given orally for 3 months. Although the device was not removed, infection did not recur during a 24‐month follow‐up.
Turkisher et al. (Mon,) conducted a case report in Infected implantable cardioverter defibrillator (n=1). Oral fusidic acid and rifampin without device removal was evaluated on Infection recurrence. Treatment of an infected implantable cardioverter defibrillator with oral fusidic acid and rifampin for 3 months without device removal resulted in no infection recurrence over 24 months.