ICU readmission was associated with significantly higher in-hospital mortality (24.7% vs 4.0%; OR 7.5, 95% CI 6.8-8.3), though hospital readmission rates did not correlate with adjusted mortality.
Cohort (n=103,984)
Yes
ICU patients (n=103,984)
ICU readmission vs No ICU readmission
In-hospital mortality — OR 7.5 (6.8-8.3), p=<0.001
Effect estimate: OR 7.5 (95% CI 6.8-8.3)
Absolute Event Rate: 24.7% vs 4%
p-value: p=<0.001
BACKGROUND: Although patients readmitted to intensive care units (ICUs) typically have poor outcomes, ICU readmission rates have not been studied as a measure of hospital performance. OBJECTIVES: To determine variation in ICU readmission rates across hospitals and associations of readmission rates with other ICU-based measures of hospital performance. RESEARCH DESIGN: Observational cohort study. SUBJECTS: One hundred three thousand nine hundred eighty four consecutive ICU patients who were admitted to twenty eight hospitals who were then transferred to a hospital ward in those 28 hospitals. MEASURES: Predicted risk of in-hospital death and ICU length of stay (LOS) were determined by a validated method based on age, ICU admission source, diagnosis, comorbidity, and physiologic abnormalities. Severity-adjusted mortality rates, LOS, and readmission rates were determined for each hospital. RESULTS: One or more ICU readmissions occurred in 5.8% patients who were initially classified as postoperative and in 6.4% patients who were initially classified as nonoperative. In-hospital mortality rate was 24.7% in patients who were readmitted as compared with 4.0% in other patients (P < 0.001). After adjusting for predicted risk of death, the odds of death remained 7.5 times higher (OR 7.5, 95% CI, 6.8-8.3). Readmitted patients also had longer (P < 0.001) ICU LOS (5.2 vs. 3.7 days) and hospital LOS (29.3 vs. 11.7 days). Severity-adjusted readmission rates varied across hospitals from 4.2% to 7.6%. Readmission rates were not correlated with severity-adjusted hospital mortality, ICU LOS, or hospital LOS. CONCLUSIONS: ICU patients who were subsequently readmitted have a higher risk of death and longer LOS after adjusting for severity of illness. However, readmission rates were not associated with severity-adjusted mortality or LOS. Those data indicate that ICU readmission may capture other aspects of hospital performance and may be complementary to these measures.
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Gregory S. Cooper
University of Notre Dame
Carl Sirio
Ospedali Riuniti di Ancona
Armando J. Rotondi
Università Cattolica del Sacro Cuore
Medical Care
Case Western Reserve University
University Hospitals of Cleveland
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Cooper et al. (Thu,) conducted a cohort in ICU patients (n=103,984). ICU readmission vs. No ICU readmission was evaluated on In-hospital mortality (OR 7.5, 95% CI 6.8-8.3, p=<0.001). ICU readmission was associated with significantly higher in-hospital mortality (24.7% vs 4.0%; OR 7.5, 95% CI 6.8-8.3), though hospital readmission rates did not correlate with adjusted mortality.
synapsesocial.com/papers/6a1734ccd17772c818bb88e9 — DOI: https://doi.org/10.1097/00005650-199904000-00009