Two male patients with underlying malignancies experienced unusual acute and subacute coronary stent thromboses, suggesting malignancy may act as a precipitating prothrombotic factor.
Case Report (n=2)
No
Highlights the increased risk and complexity of acute stent thrombosis in patients with concurrent malignancy undergoing PCI, suggesting a need for rigorous precautions in revascularization and anti-platelet therapy.
There have been a growing numbers of patients diagnosed with malignancy and coronary artery disease simultaneously or serially. In the era of percutaneous coronary intervention (PCI), stent thrombosis has been a rare but challenging problem. Recently, we experienced two unique cases of acute stent thrombosis in patients with malignancy. The first case showed acute and subacute stent thrombosis after PCI. The second case revealed simultaneous thromboses in stent and non-treated native coronary artery. We believe that we need rigorous precautions in the treatment of patients with coronary artery disease and malignancy, especially with regards to deciding how and whether to revascularize, as well as which anti-platelet agents to select.
Lee et al. (Sun,) conducted a case report in Acute coronary stent thrombosis with concomitant malignancy (n=2). Percutaneous coronary intervention was evaluated. Two male patients with underlying malignancies experienced unusual acute and subacute coronary stent thromboses, suggesting malignancy may act as a precipitating prothrombotic factor.