July 3, 2007Open Access

Extra-embryonic endoderm cells derived from ES cells induced by GATA Factors acquire the character of XEN cells

DSDaisuke ShimosatoRIKEN Center for Computational Science MSMakoto ShikiRIKEN Center for Computational Science HNHitoshi NiwaOsaka Dental University

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Abstract

We show here that Gata-induced extra-embryonic endoderm cells derived from ES cells mimic the character of XEN cells. These findings indicate that Gata transcription factors are sufficient for the derivation and propagation of XEN-like extra-embryonic endoderm cells from ES cells.

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